Tuesday, April 22, 2008

U-M Looking for Anxiety Volunteers After THC Trial

The University of Michigan Research Clinic recently completed a study on the effects of THC in relation to anxiety:

In a paper last month in the Journal of Neuroscience, K. Luan Phan, M.D., and his former University of Chicago colleagues reported intriguing findings from a brain imaging study in occasional, non-dependent, marijuana users.

In a placebo-controlled design, they made the findings after giving the volunteers delta-9-tetrahydrocannabinol (THC), the active ingredient in marijuana, and exposing them to photographs of emotional faces, which served as signals of social communication. The study results, which showed that THC reduces the response to threat in a brain region called the amygdala, allowed the researchers to zero in on an area of the brain that might serve as a good target for new anti-anxiety drugs.

Now, with a new clinical trial that is currently seeking participants, Phan is searching for more clues as to how anxiety treatment could be tailored to the individual patient, to give the best chance that a treatment will work for him or her.

Now they are looking for people with Anxiety disorders to test the effects of sertraline, better known as Zoloft, to see what effects this selective serotonin reuptake inhibitor has on the human brain. U-M is looking for volunteers, so if you are in their area, and suffer an anxiety disorder, why not contact them.