For many years, I have been reading and seeing documentaries about the cure for many cancers. I've read about it on pro-pot websites. I've seen documentaries about people who have been using cannabis to treat and cure cancers and other diseases. I've read countless research findings that show cannabinoids to be superior to all other cancer treatments. I'm not talking about relieving the symptoms of chemotherapy, which it is globally recognised to do. I'm not talking about cannabis and its analgesic effects for cancer pain and other conditions.
I am talking about cannabis CURING cancer. YES, CURING!!! Did you see that word. It says curing. It is derived from the verb 'cure'. To make healthy again.
Almost every day, new research is showing that cannabinoids can stop the spread of various types of cancers, AND 'kill' the surviving cancer cells without harming healthy cells.
Before I go onto the technical research jargon, in very simple terms this is basically how cannabinods kill cancer:
The cannabinoids somehow block the cancer cells ability to 'feed' and 'breath'. As with anything, cancer cells need to get nutrients in order to multiply. Cannabinoids not only prevent the cells from multiplying, but essentially starve the cells to death.
The kicker is that cannabinoids do not target healthy cells. Anyone who has experience with chemotherapy knows what damage that treatment does to healthy cells.
Let's look at some of the evidence. I'm going to take you on a little journey through scientific research and anecdotal accounts of how cannabis cures cancer. I'll also provide some food for thought as to why there hasn't been a global recognition and acceptance of cannabis as a cancer cure.
I am going try to stick with research papers released in the past two years. Yes, there are many studies that have been conducted over the years. They've been reported many times in the pro-cannabis press and in this blog. I want to show you the new stuff. I'll also decipher the abstracts into human language...
This research has all been conducted in the last couple of years and reflects research conducted in past years. These studies also come from all over the globe.
Cannabinoids May Cure Gastric Cancer
Although cannabinoids are associated with antineoplastic activity in a number of cancer cell types, the effect in gastric cancer cells has not been clarified. In the present study, we investigated the effects of a cannabinoid agonist on gastric cancer cell proliferation and invasion. The cannabinoid agonist WIN 55,212-2 inhibited the proliferation of human gastric cancer cells in a dose-dependent manner and that this effect was mediated partially by the CB1 receptor. We also found that WIN 55,212-2 induced apoptosis and down-regulation of the phospho-AKT expression in human gastric cancer cells. Furthermore, WIN 55,212-2 treatment inhibited the invasion of gastric cancer cells, and down-regulated the expression of MMP-2 and VEGF-A through the cannabinoid receptors. Our results open the possibilities in using cannabinoids as a new gastric cancer therapy. J. Cell. Biochem. 110: 321-332, 2010. © 2010 Wiley-Liss, Inc.
Translation (my comments in brackets):
These scientists knew that cannabinoids could effectively fight other cancer types, but no one had done any tests on gastric cancers specifically. So they got a hold of some synthetic cannabinoids (why synthetic? I assume because natural cannabinoids have such restrictions in terms of access for research).
They tested the cannabinoids on human gastric cancer cells at different doses and found that at a particular dose and balance of cannabinoids, the cancer cells died.
Definitions (from Wikipedia and Wordweb):
Antineoplastics are drugs that inhibit and combat the development of neoplasms.
A type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival.
Cannabinoids Cure Muscular Cancers?
According to this research, yes:
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma
Gene expression profiling has revealed that the gene coding for cannabinoid receptor 1 (CB1) is highly up-regulated in rhabdomyosarcoma biopsies bearing the typical chromosomal translocations PAX3/FKHR or PAX7/FKHR. Because cannabinoid receptor agonists are capable of reducing proliferation and inducing apoptosis in diverse cancer cells such as glioma, breast cancer, and melanoma, we evaluated whether CB1 is a potential drug target in rhabdomyosarcoma. Our study shows that treatment with the cannabinoid receptor agonists HU210 and Δ9-tetrahydrocannabinol lowers the viability of translocation-positive rhabdomyosarcoma cells through the induction of apoptosis. This effect relies on inhibition of AKT signaling and induction of the stress-associated transcription factor p8 because small interfering RNA–mediated down-regulation of p8 rescued cell viability upon cannabinoid treatment. Finally, treatment of xenografts with HU210 led to a significant suppression of tumor growth in vivo. These results support the notion that cannabinoid receptor agonists could represent a novel targeted approach for treatment of translocation-positive rhabdomyosarcoma. [Mol Cancer Ther 2009;8(7):1838–45]
These scientists tested cannabinoids against a particular muscular cancer and got the same results as the Koreans that tested them against gastric cancer.
From the United States of America
Let's Put an End to Breast Cancer
More and more studies are proving that cannabinoids actively fight breast cancers. WHY are women still having to have mastectomies?
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
Cannabinoids have been reported to possess antitumorogenic activity. Not much is known, however, about the effects and mechanism of action of synthetic nonpsychotic cannabinoids on breast cancer growth and metastasis. We have shown that the cannabinoid receptors CB1 and CB2 are overexpressed in primary human breast tumors compared with normal breast tissue. We have also observed that the breast cancer cell lines MDA-MB231, MDA-MB231-luc, and MDA-MB468 express CB1 and CB2 receptors. Furthermore, we have shown that the CB2 synthetic agonist JWH-133 and the CB1 and CB2 agonist WIN-55,212-2 inhibit cell proliferation and migration under in vitro conditions. These results were confirmed in various mouse model systems. Mice treated with JWH-133 or WIN-55,212-2 showed a 40% to 50% reduction in tumor growth and a 65% to 80% reduction in lung metastasis. These effects were reversed by CB1 and CB2 antagonists AM 251 and SR144528, respectively, suggesting involvement of CB1 and CB2 receptors. In addition, the CB2 agonist JWH-133 was shown to delay and reduce mammary gland tumors in the polyoma middle T oncoprotein (PyMT) transgenic mouse model system. Upon further elucidation, we observed that JWH-133 and WIN-55,212-2 mediate the breast tumor-suppressive effects via a coordinated regulation of cyclooxygenase-2/prostaglandin E2 signaling pathways and induction of apoptosis. These results indicate that CB1 and CB2 receptors could be used to develop novel therapeutic strategies against breast cancer growth and metastasis. [Mol Cancer Ther 2009;8(11):3117–29]
Translation: Cannabinoids inhibit the spread of, and kill breast cancer cells.
Combined research from Italy and the US
Do you know someone with intestinal cancer? Has their doctor told them of this research?
Cannabinoids in Intestinal Inflammation and Cancer
Emerging evidence suggests that cannabinoids may exert beneficial effects in intestinal inflammation and cancer. Adaptive changes of the endocannabinoid system have been observed in intestinal biopsies from patients with inflammatory bowel disease and colon cancer. Studies on epithelial cells have shown that cannabinoids exert antiproliferative, antimetastatic and apoptotic effects as well as reducing cytokine release and promoting wound healing. In vivo, cannabinoids – via direct or indirect activation of CB1 and/or CB2 receptors – exert protective effects in well-established models of intestinal inflammation and colon cancer. Pharmacological elevation of endocannabinoid levels may be a promising strategy to counteract intestinal inflammation and colon cancer.I don't think I need to translate that abstract.
From The United Arab Emirates and the US
Mouth Cancer is highly resistant to accepted anti-cancer drugs. Cannabinoids kill it.
Cannabinoids Inhibit Cellular Respiration of Human Oral Cancer Cells
Background and Purpose: The primary cannabinoids, Δ9-tetrahydrocannabinol (Δ9-THC) and Δ8-tetrahydrocannabinol (Δ8-THC) are known to disturb the mitochondrial function and possess antitumor activities. These observations prompted us to investigate their effects on the mitochondrial O2 consumption in human oral cancer cells (Tu183). This epithelial cell line overexpresses bcl-2 and is highly resistant to anticancer drugs. Experimental Approach: A phosphorescence analyzer that measures the time-dependence of O2 concentration in cellular or mitochondrial suspensions was used for this purpose. Key Results: A rapid decline in the rate of respiration was observed when Δ9-THC or Δ8-THC was added to the cells. The inhibition was concentration-dependent, and Δ9-THC was the more potent of the two compounds. Anandamide (an endocannabinoid) was ineffective; suggesting the effects of Δ9-THC and Δ8-THC were not mediated by the cannabinoidreceptors. Inhibition of O2 consumption by cyanide confirmed the oxidations occurred in the mitochondrial respiratory chain. Δ9-THC inhibited the respiration of isolated mitochondria from beef heart. Conclusions and Implications: These results show the cannabinoids are potent inhibitors of Tu183 cellular respiration and are toxic to this highly malignant tumor.
Copyright © 2010 S. Karger AG, Basel
Translation: (Surprise, surprise) cannabinoids kill mouth cancer cells.
The following article covers recent research into the role of cannabinoids in anti-cancer therapies:
Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents
Cannabinoids (the active components of Cannabis sativa) and their derivatives have received renewed interest in recent years due to their diverse pharmacological activities. In particular, cannabinoids offer potential applications as anti-tumour drugs, based on the ability of some members of this class of compounds to limit cell proliferation and to induce tumour-selective cell death. Although synthetic cannabinoids may have pro-tumour effects in vivo due to their immunosuppressive properties, predominantly inhibitory effects on tumour growth and migration, angiogenesis, metastasis, and also inflammation have been described. Emerging evidence suggests that agonists of cannabinoid receptors expressed by tumour cells may offer a novel strategy to treat cancer. In this chapter we review the more recent results generating interest in the field of cannabinoids and cancer, and provide novel suggestions for the development, exploration and use of cannabinoid agonists for cancer therapy, not only as palliative but also as curative drugs.
I'll move on now. However, if you're interested in lung cancer research, look here
If glioma (brain cancers etc) is your thing, check this
There are many more studies that show how cannabis can cure and treat many diseases besides cancer. I'll expand on this in future posts.
Anecdotal, long term evidence.
There is so much junk on YouTube and other multimedia websites, that it can be hard to find real documented information in respect to cannabis. Yes, you can find lots of grow videos and other stuff, but the true stories are sometimes hard to find.
The following website and links to video content are about Rick Simpson, a man who has been treating his family and friends with cannabis oil for many years. He has seen first-hand the results that his oil has had on various forms of cancer and other diseases. Rick Simpson does not sell his product. He gives his medicine away. Rick is currently 'in exile' in Europe. If he returns to Canada, he may be jailed and denied the medicine he uses to keep him alive. I urge you to read his story and watch the documentary if you haven't before.
Rick Simpsons Website- Phoenixtears.ca
If I return home, I will be arrested and put in jail without bail or medicine. I am not afraid of their jails but I cannot go without my medicine, the system has nothing that could help me with my conditions. So for me to return to Canada would be like committing suicide. I would be thrown in jail and denied my medicine and a short time later you would hear in the news that Rick Simpson died of natural causes. I cannot tell the people of Canada who are depending on my presence to help their medical conditions how sorry I am. But it was not me who caused this situation.
It seems the goal is to keep me from returning home and they succeeded. But to what end? All hemp magazines on this planet are now telling their readers how to heal themselves with this wonderful medicine. If governments want to live in denial, it will be short-lived. We are gaining tens of thousands of followers every day. You cannot stop the truth.
For me, going to the Cannabis Cup was a great adventure and I would like to thank Greenhouse Seeds for making this trip possible. To stand before hundreds of people and being crowned as the Freedom Fighter of the Year was a great honour. But it is an honour that comes with a price. Most people who have worn the tricorn hat have gone to jail for spreading the truth.
To have this honour bestowed on me and to join the ranks of people like Jack Herer and Eddy Lepp has given my life even more purpose.
Jack Herer believed as I do that the key to hemp´s complete legalisation is in the magnificent medicine this plant can produce. Once the public becomes aware of the fact that properly made hemp medicine can cure or control practically any medical condition, who is going to stand against the use of hemp?
Rick has a number of videos that are worth watching. The 'Run From The Cure' documentary is a must see:
Rick Simpson Videos
I hope this post opens the minds of many who were ignorant of cannabis as a cancer cure, and provides some information and entertainment for the already aware.